Hepatitis C Damage Doesn’t Stop at the Liver, Renal Failure Risk Seen

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A new study of chronic kidney disease (CKD) patients shows untreated hepatitis C virus infection (HCV) leads to a more precipitous decrease in kidney function, a decline more likely to become end-stage renal disease (ERD)

Reporting at IDWeek 2016 in New Orleans, LA, Sara Tartof, PhD, MPH, of the Kaiser Permanente Southern California (KPSC) Research & Evaluation Department in Pasadena, CA, and colleagues found CKD patients with untreated HCV were one and a half times more likely to suffer 25% decrease in the estimated glomerular filtration rate (eGFR) and 2.5 times more likely to develop ERD.

The Impact of Untreated Hepatitis C Infection on Progression of Renal Decline among Patients with Chronic Kidney Disease, compares data on 150,712 CKD patients and 1,706 with both HCV CKD.  Patient data included men and women aged 18 and older diagnosed from 2004-2014 at Kaiser Permanente in southern California and Mid-Atlantic states.

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