Platelet count recovers after SVR in HCV, disrupted by HBV coinfection

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Patients treated for hepatitis C who achieved sustained virologic response recovered platelet counts, according to recently published data. Hepatitis B coinfection, however, disrupted platelet count recovery, especially in patients with advanced liver disease from chronic HCV.

“Taken collectively, it is postulated that the factors associated with [platelet] recovery may be linked to fibrotic regression,” the researchers wrote. “Interestingly, we noticed that HBV co-infection was associated with slow [platelet] recovery. The result hints that HBV co-infection may interfere with fibrotic regression in patients with curative HCV infection.”

Of particular note was that the condition existed only in patients with advanced liver disease.

Read more….https://www.healio.com/hepatology/hepatitis-c/news/online/%7B3d832250-e45d-4e8a-8bcd-1847833fe016%7D/platelet-count-recovers-after-svr-in-hcv-disrupted-by-hbv-coinfection